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RETATRUTIDE

Precision-formulated metabolic support peptide

Retatrutide is known as a triple receptor agonist because it targets three seperate metabolic hormone receptors simultaneously:

1. GLP-1 receptor

2. GIP receptor

3. Glucagon receptor

This combined mechanism is what makes retatrutide different from earlier peptide therapies.

1.

GLP-1
RECEPTOR
Appetite & Glucose Regulation 

GLP-1 is a hormone released after eating. Activation may help:

Reduced appetite

Increase satiety 

Slow gastric emptying

Support insulin secretion

Reduced food intake

WHY THE 3 RECEPTORS MATTER

Most peptides target 1 or 2 receptors.

Retarutide targets all 3 simultaneously, which may provide enhanced 

metabolic support.

APPETITE CONTROL

Helps reduce hunger and increase feelings of fullness.

METABOLIC OPTIMISATION

Supports glucose regulation, insulin response and efficient nutrient use.

ENERGY & FAT UTILISATION

Supports increased energy expenditure and fat loss.

2.

Insulin Response & Metabolic Support

GIP supports nutrient metabolism.

Activation may help:

Enhance insulin release

Improve glucose control

Support nutrient utilisation

Promote fat metabolism 

Support overall metabolism

GIP
RECEPTOR
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3.

GLUCAGON RECEPTOR
Energy Expenditure & Fat Metabolism

The glucagon receptor in retatrutide.

Activation may help:

Increased energy expenditure

Enhanced fat oxidation

Promote lipolysis (fat breakdown)

Support metabolic activity

Aid in weight managment

TIRZEPATIDE

Precision-formulated metabolic support peptide

Trizepetide is a dual receptor agonist that targets GIP and GLP-1 receptors simultaneosly, helping to support blood sugar control, appetite regulation and metabolic health.

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2.

Insulin Response & Metabolic Support

GIP supports nutrient metabolism.

Activation may help:

Enhance insulin release

Improve glucose control

Support nutrient utilisation

Promote fat metabolism 

Support overall metabolism

GIP
RECEPTOR
WHY THE 2 RECEPTORS MATTER

Early peptide therapies target 1  receptor.

Trizepatide targets 2 receptors simultaneously, which may provide enhanced metabolic support.

metabolic support.

APPETITE CONTROL

Helps reduce hunger and increase feelings of fullness.

METABOLIC OPTIMISATION

Supports glucose regulation and efficent nutrient use.

ENERGY & FAT UTILISATION

Supports improved fat metabolism and energy utilisation as part of metabolic pathways.

1.

GLP-1
RECEPTOR
Appetite & Glucose Regulation 

GLP-1 is a hormone released after eating. Activation may help:

Reduced appetite

Increase satiety 

Slow gastric emptying

Support insulin secretion

Reduced food intake

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CAGRILINITIDE

Precision-formulated metabolic support peptide

Cagrlinitide is an amylin analogue peptide designed to support appetite regulation and metabolic signalling pathways associated with satiety and gastric emptying.

1.

AMYLIN ANALOGUE
PATHWAY
Appetite & Glucose Regulation 

Amylin is a naturally occuring hormone released alongside insulin after eating.

Activation may help

Support appetite regulation

Increase satiety

Slow gastric emptying 

Support reduced food intake

Support metabolic signalling

CAGRILINITIDE
AMYLIN ANALOGU

Targeted Approach

Cagrilinitide mimics the action of amylin, a hormone involved in satiety and gastric emptying.

Distinct Mechanism

Works through amylin-associated signalling pathways, complementary to incretin-based therapies.

Purpose-Driven

Designed to support appetite control and metabolic signalling for long-term weight management goals.

WHY THE PATHWAY MATTERS 

Traditional peptide therapies often focus on incretin pathways.

APPETITE REGULATION

Supports increased feelings of fullness and appetite.

GASTRIC EMPYING

Supports slower gastric emptying and prolonged satiety.

METABOLIC SUPPORT

Supports metabolic signalling associated with nutrient intake.

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